The concept of accessibility has been the subject of research by many researchers in terms of measurement and quantification, which depending on the purpose and needs of the researcher can be measured through many indicators and methods. In this research, we in order to quantify the accessibility of the Municipality of Zitsa, an accessibility model has been developed, exclusively for Zitsa, by using the general form of the gravity-based models.  The research indicates that the combination of a weighted activity function and the travel cost adjusted with Distance Decay offer the more representative accessibility/ remoteness results for the municipality of Zitsa. The developed model is customized for the characteristics of the area, since a special analysis has taken place to identify all the relevant infrastructures and services inside the municipality as well as the surrounding regions. Finally, we show the impact of remoteness in two important aspects of regional development – the human capital and the economy.