This paper investigates the possibility of enhancement and promotion of Derveni historic trail that used to connect Greece with Albania, as a contemporary cycling route. The aim is to attract visitors in the region of Pogoni and to create a space for the residents to find opportunities to come in contact with natural environment and their culture. The object of this paper is a design study of the rail’s central part and the documentation of proposed interventions at it. The interventions are based on their incorporation to the local natural environment and the promotion of local cultural elements. The rail is enhanced and becomes a pole of attraction for recreation activities. At the same time, the cost of the proposed interventions is estimated. In addition, the importance of further promotion of the trail is documented based on relative European examples and several specific actions are suggested to the direction of Derveni’s trail touristic promotion.