The abandonment of buildings is typical of mountain areas, as a result of population decline, thus weakening the social structure. The changes that drained human life from the mountainous regions left vacant buildings or whole villages abandoned. The villages of Zagori region represent a net of settlements characterised by remarkable and well-preserved vernacular architecture. However, scattered throughout the region there are many buildings not housing any use that have been abandoned and already damaged at an important level. Some of these are rare examples of local architecture with significant cultural value at national level. In this study, the basic meanings of land, property and the importance of rehabilitation of public buildings are initially, compendiously, presented. The object of this study is the documentation of proposals for the re-use of some of the abandoned buildings in the region of Zagori. The proposed new uses are aiming at the area’s enhancement and the further development of the area’s attractiveness and value. The study is aiming at revealing the importance of re-using old buildings as well as at the utilization of proposed building uses as pilot case studies in the frame of a general development plan for the rehabilitation of all existing abandoned buildings.